Clinical Services – Flow Cytometry

Flow Cytometry is a process that allows for the individual measurement of cell fluorescence and light scattering; providing a rapid method to identify and classify individual cells, as well as the characterization of large populations of cells. 

NeoloMed offers immunophenotyping by flow cytometry, an important tool in the diagnosis and prognosis of patients with certain types of cancer. Our flow cytometry testing is used in conjunction with classical cytogenetic analysis in the diagnosis of oncology-related indications.

In the bone marrow, normal blood cells develop from stem cells branching into distinct cell populations (for example: T cell and B cell populations).  Each cell population has a unique maturation pathway. At each stage of development, the cells carry a distinctive set of markers classified by the CD (cluster of differentiation) nomenclature. Malignancies can arise at different stages in the development of a cell. Leukemias and lymphomas will express a specific set of markers (or in the case of leukemias, lack certain markers or express aberrant proteins) depending on the stage and pathway of differentiation and they are classified accordingly.

NeoloMed evaluates each patient sample with a panel of antibodies – the selection of which is dependent on the initial clinical diagnosis.

Currently, NeoloMed provides the following testing panels:
  • Lymphoid
  • PNH
  • ZAP-70
  • Myeloid/Lymphoid and Acute Leukemia
  • Multiple Myeloma
  • Clinical Flow Cytometry
    We will work with our clients to validate additional antibodies if the results from the initial screen indicate a need for further classification or there is a need for a panel that is more specific for a particular disease type.
     
    Cap Accredited